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The DeLIVER programme covers 3 clinical research studies (DELPHI, SELiNa and Pearl) that aim to provide a better understanding on why changes within the liver (and in case of DELPHI also the bile ducts and pancreas) can lead to cancer and identify markers that detect liver cancer at the earliest stages when curative therapies may be applied. The clinical research studies recruit patients over the age of 18 years with liver conditions and/or liver cancer from NHS sites in England. The DELPHI study is further recruiting patients with conditions or cancer affecting the bile duct or pancreas.